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Mounjaro and Alcohol: 7 Helpful Things to Know Before You Drink

Wondering if Mounjaro and Alcohol are okay? Let’s look at the details to help better understand this combination.

If you are currently using Tirezepatide (Mounjaro) and are wondering if it is safe to drink alcohol, we are diving into everything we have learned from personal experience as well as what a doctor has to say in regards to the matter.

What to Know About Mounjaro and Alcohol

Personally, I am more of a social drinker. While I don’t drink at home, when out to eat or with friends, I will enjoy a cocktail or glass of wine. Before ingesting, something I had failed to think about what combining Mounjaro and alcohol.

mounjaro and alcohol information what to know before you drink
mounjaro and alcohol

Chances are, unless you are sober – the thought might have crossed your mind. Let’s get into it and find out the deets before drinking.

If you are using Mounjaro for type 2 diabetes, check with your doctor for specific information in regards to interaction and indications with your personal health record. This information is being provided from personal experiences with just Mounjaro and alcohol, not any other drug.

Here are 5 helpful things to know about Mounjaro and drinking alcohol.

It is Safe to Drink Alcohol

There are no indications in regards to drinking alcohol on Mounjaro. That said, there are several things you should know before you do so.

safe drink on mounjaro
safe drink on mounjaro

We are breaking down the facts and while it’s safe, it’s important to know that the alcohol can effect a body differently when using Mounjaro.

Quicker Effects

With the changes to how your body digestion works with Mounjaro, a noticeable effect when drinking alcohol is that the liquor hits quicker. While you may have 3 drinks before noticing the liquor, don’t expect that to remain the same when using Tirezepatide.

mounjaro alcohol effects
mounjaro alcohol effects

Remember that Mounjaro works by slowing the gastric emptying. With less food in your body, the alcohol hits a lot sooner than before.

Personally, even the one alcoholic drink buzz feels different. It’s like my body on Mounjaro is just telling me that the love affair with alcohol is over. (As much of a alcohol love affair that a one-drink gal like myself can have!)

Hangover Hell

Following up on the liquor hits quicker statement, let’s talk about hangover hell. The worse hangover I’ve had has been after drinking 3 cocktails over the course of a 6 hour party.

hangover hell
hangover hell

Possibly due to how the alcohol absorption works when on Mounjaro – if you drink more than your “new” body can tolerate – the hangover will find you and it is not pretty.

Alcohol is a Diuretic

Even without Mounjaro, we all know the risks of dehydration and alcohol. Alcohol’s diuretic properties cause dehydration by accelerating the removal of excess water and sodium from your body.

When you drink alcohol, your renal system, including your kidneys, ureters, and bladder, works to eliminate fluids from your bloodstream more rapidly than with other beverages. Failing to hydrate while consuming alcohol can lead to rapid dehydration.

All that said, when putting Mounjaro and alcohol together, make sure that you have plenty of water and stay hydrated.

Before You Drink on Mounjaro

The best thing to do before drinking on Mounjaro is to prepare your body. While we now know it’s safe, the risks and effects – let’s talk about what we can do if we know we are going to want alcohol.

before you drink on mounjaro
before you drink on mounjaro

Hydration is Key

As we mentioned about, the key thing with Mounjaro and alcohol is that hydration is critical. Make sure that your water intake has your body hydrated before consuming alcohol. In addition to hydration, you will want to ensure that you have had an adequate amount of calories and protein.

In addition to hydration and making sure that you are consuming adequate calories to help in the absorption of alcohol – make sure that you limit how much alcohol you consume.

Reduced Alcohol Cravings

There is ongoing conversations in regards to how GLP-1 such as Mounjaro and Ozempic are reducing alcohol cravings.

reduced alcohol cravings
reduced alcohol cravings

While we specifically here talk about our experience with Mounjaro for weight loss, do talk to your doctor if this is something that would be of interest to your health journey.

Alcohol Tastes Different

Personally, an unintentional but not bad side effect of Mounjaro is just not wanting alcohol. The delicious margarita on the menu at Uncle Julios doesn’t even sound appealing.

mounjaro alcohol aversion
mounjaro alcohol aversion

Alcohol doesn’t taste the same. This is true with many foods on Mounjaro, though.

GLP-1 Alcohol Cravings

While some might say, Mounjaro has a general effects in not wanting things – doctors are using this lessened desire to explore potential opportunities to use GLP-1 for a variety of addictions. Studies are being done to see if GLP-1 is something that could help not only with alcohol cravings, but a wide array of other additions as well. (source:

Risks While Drinking on Mounjaro

While there are no indications stating that you can’t drink alcohol on Mounjaro, like anytime you drink – there are risks. With being on Tirezepatide, your body processes food differently so how it reacts to alcohol will not be the same as before.

risks while drinking on mounjaro
risks while drinking on mounjaro

This is why above we said to make sure that you have food in your stomach and that you are hydrated.

Dr. Salas with New York Endocrinology suggests not combining Mounjaro and alcohol if you have a history of pancreatitis.

Mounjaro Wine and Acid Reflux

There are multiple angles to if drinking wine helps reduce or increases reflux. That said, many people on Mounjaro have stated they have noticed drinking wine they have had an increase in reflux.

Mounjaro Wine and Acid Reflux
Mounjaro Wine and Acid Reflux

The alcohol generates more production of acid in your stomach which can result in acid reflux. While there is not an absolute answer as to if drinking wine on Mounjaro will cause you acid reflux, take note in the event this is something that you experience.

Takeaways about Mounjaro and Alcohol

From our personal experience with alcohol and Mounjaro, as well as talking to several others here are the main takeaways:

  • Liquor hits quicker.
  • Make sure to not drink on an empty stomach.
  • Drink water and replenish electrolytes before and while drinking alcohol.
  • Don’t over drink and if you do, don’t be surprised by the hangover.
  • If you experience a weight stall on Mounjaro, cut back on the alcohol as it may be the root cause.
  • Moderation is key. Lesser is better.
mounjaro alcohol takeaways
mounjaro alcohol takeaways

There are numerous people we have talked to who can testify that they just can’t drink much anymore because of either the liquor hitting too quick or experiencing the worse hangover after drinking on Mounjaro.

Pace your drinks, limit your consumption. Moderation is key. Cheers!

Who should not drink alcohol while on Mounjaro?

From You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis.

What are alcoholic alternatives?

If you are out and about but don’t care to see how your body reacts to alcohol while on Tirezepatide, try a mocktail! Zero proof drinks are becoming more common in bars and restaurants. These are cocktails and drinks made with no alcohol. Enjoy all the taste without the risk or guilt!

What are the biggest Mounjaro alcohol side effects?

While regardless of what you are taking, drinking alcohol has side effects – with Mounjaro people who take it state that they cannot drink as much due to feeling the effects quicker as well as experiencing a hangover the next day with fewer drinks. Others state they feel nauseous or throw up after consuming alcohol and Tirezepatide. Read more about Mounjaro side effects and note that every person is different and how your body reacts maybe different.

This information is for educational use only. Any medical advice should be discussed specifically between you and your medical professional. Information provided here is not

We are excited to expand our keto content to include other solutions our community is using to achieve optimal health. While we understand that this may not be for everyone, we do know that people are seeking information about obesity as a disease and solutions, such as Wegovy, Ozempic / Semaglutide and Mounjaro / Tirezepatide / Zepbound.

Please direct any questions in regards to personal use with your doctor and any questions in regards to coupons, etc should be discussed with your pharmacy or with the pharmaceutical customer service.

5 Things to Know Before You Drink: Mounjaro and Alcohol is part of the Keto Dirty series on Tirzepatide

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